TBC1D30

Across TCGA cell cohorts, TBC1D30 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TBC1D30-associated genes across cancer lineages are CCL16, SMCP, and TGM7. Each is linked with TBC1D30 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D30-to-partner and partner-to-TBC1D30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL16 grouped by TBC1D30-low versus TBC1D30-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D30→partner) and Y-score (partner→TBC1D30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CCL16 →	+0.030	+4.807	<.001	.006	3	1
CNS	SMCP →	+0.114	+5.321	<.001	.005	3	1
LUNG_NSCLC_LUAD	TGM7 →	+0.006	+4.887	<.001	.009	3	1
LARGE_INTESTINE	C6orf118 →	+0.163	+4.378	<.001	<.001	3	1
LARGE_INTESTINE	DEFA4 →	+0.022	+3.700	<.001	.009	3	1
LARGE_INTESTINE	ELOA3DP →	+0.022	+3.103	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

CCL16 by TBC1D30 expression — BLOOD_Myeloma

Explore this box plot interactively →