TBC1D29P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TBC1D29P Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TBC1D29P data layer compared with 21 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher TBC1D29P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TBC1D29P expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

OV, SKCM, and TGCT are the cancer types where TBC1D29P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVOSMedianII,III,IV0.1800.844<.00136view →
SKCMDFSMedianII,III,IV1.0000.558.01611view →
TGCTDFSMedianAll0.0810.801.0056view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TBC1D29P–OV (OS)

Kaplan–Meier survival curve for TBC1D29P mutant vs wild-type samples in OV.

Open the OV breakdown →

Exploration