TBC1D29P

Across TCGA patient cohorts, TBC1D29P mutation is significantly associated with the RNA expression of many other genes, with 65 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D29P-associated genes across cancer lineages are RNU6-492P, RNU6-6P, and RNA5SP489. Each is linked with TBC1D29P in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D29P-to-partner and partner-to-TBC1D29P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-492P grouped by TBC1D29P-low versus TBC1D29P-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D29P→partner) and Y-score (partner→TBC1D29P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	2
UCEC	RNU6-6P →	+0.595	+3.227	.001	.001	3	2
COAD	RNA5SP489 →	+0.518	+7.741	<.001	.009	3	2
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	1
HNSC	TSPY7P →	+0.039	+7.954	<.001	.008	3	1
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

RNU6-492P by TBC1D29P expression — HNSC

Explore this box plot interactively →