TBC1D29P

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TBC1D29P mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBC1D29P-associated genes across cancer lineages are LCE1C, SLC5A8, and OR10A6. Each is linked with TBC1D29P in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D29P-to-partner and partner-to-TBC1D29P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE1C grouped by TBC1D29P-low versus TBC1D29P-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D29P→partner) and Y-score (partner→TBC1D29P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaLCE1C →+0.432+4.922.002.00931
BLOOD_LeukemiaSLC5A8 →+0.182+5.201<.001.00631
BLOOD_LeukemiaOR10A6 →+0.044+5.201<.001.00631
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

LCE1C by TBC1D29P expression — BLOOD_Leukemia

Box plot of LCE1C in TBC1D29P-low vs TBC1D29P-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration