Across TCGA cell cohorts, TBC1D26 mutation is significantly associated with the mutation status of many other genes, with 435 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBC1D26-associated genes across cancer lineages are UGT1A10, INSM1, and SLC47A2. Each is linked with TBC1D26 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D26-to-partner and partner-to-TBC1D26 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D26→partner) and Y-score (partner→TBC1D26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	UGT1A10 →	+4.824	+5.392	.004	.004	1	2
SKIN	INSM1 →	+4.824	+5.392	.004	.004	1	2
SKIN	SLC47A2 →	+4.824	+5.392	.004	.004	1	2
SKIN	TBX1 →	+5.824	+5.824	.002	.002	1	2
SKIN	SLC8B1 →	+4.239	+5.053	.007	.007	1	2
BLOOD_Leukemia	FNIP1 →	+4.736	+5.560	.003	.003	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 435 associations by consensus.

Exploration

TBC1D26 survival (RNA) · tumor vs normal (RNA) · all TBC1D26 data types