TBC1D26-AS1

Across TCGA pan-cancer cohorts, TBC1D26-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TBC1D26-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where TBC1D26-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TBC1D26-AS1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and UCEC are the cancer types where TBC1D26-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TBC1D26-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	−0.400	<.001	9	view →
LUSC	Male	All	−0.367	<.001	8	view →
UCEC	All	All	+0.170	.013	6	view →
HNSC	All	All	+0.015	.032	2	view →
ESCA	Female	All	−0.066	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

TBC1D26-AS1–LUAD

Open the LUAD breakdown →