Across TCGA patient cohorts, TBC1D25 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,167 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible TBC1D25-associated GO terms across cancer lineages are Protein demethylation, Obsolete regulation of histone methylation, and Positive regulation of mitophagy in response to mitochondrial depolarization. Each is linked with TBC1D25 in more than 28 cancer types. Because this analysis shows association rather than direction, both TBC1D25-to-partner and partner-to-TBC1D25 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D25→partner) and Y-score (partner→TBC1D25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Protein demethylation →	+0.104	+0.469	<.001	<.001	3	29
SCLC	Obsolete regulation of histone methylation →	+0.133	+0.609	<.001	<.001	3	29
SCLC	Positive regulation of mitophagy in response to mitochondrial depolarization →	+0.212	+0.811	<.001	<.001	2	29
SCLC	Obsolete histone H4 acetylation →	+0.122	+0.538	<.001	<.001	3	28
SCLC	Regulation of autophagy of mitochondrion in response to mitochondrial depolarization →	+0.134	+0.672	<.001	<.001	2	28
SCLC	Obsolete regulation of dosage compensation by inactivation of X chromosome →	+0.111	+0.672	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,167 associations by consensus.

Exploration

TBC1D25 survival (RNA) · tumor vs normal (RNA) · all TBC1D25 data types