TBC1D25

Across TCGA patient cohorts, TBC1D25 protein abundance is significantly associated with the RNA expression of many other genes, with 3,932 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TBC1D25-associated genes across cancer lineages are P4HA2, DDX6, and RN7SL301P. Each is linked with TBC1D25 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBC1D25-to-partner and partner-to-TBC1D25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D25 versus P4HA2 in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D25→partner) and Y-score (partner→TBC1D25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	P4HA2 →	+0.630	+0.219	<.001	<.001	3	3
BRCA	DDX6 →	-0.364	-0.275	.006	.003	3	2
BRCA	RN7SL301P →	+0.684	+0.238	.007	.004	3	2
GBM	PLP2 →	+1.054	+0.255	<.001	.001	3	2
GBM	SPHK2 →	-0.346	-0.282	.005	.001	3	2
LSCC	PTGES2 →	-0.501	-0.196	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,932 associations by consensus.

TBC1D25 vs P4HA2 — GBM

Explore this scatter interactively →