TBC1D25

Across TCGA cell cohorts, TBC1D25 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,543 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBC1D25-associated GO terms across cancer lineages are Growth hormone secretion, Regulation of autophagosome maturation, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with TBC1D25 in more than 15 cancer types. Because this analysis shows association rather than direction, both TBC1D25-to-partner and partner-to-TBC1D25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Growth hormone secretion grouped by TBC1D25-low versus TBC1D25-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D25→partner) and Y-score (partner→TBC1D25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Growth hormone secretion →	+0.147	+1.120	<.001	<.001	3	16
URINARY_TRACT	Regulation of autophagosome maturation →	+0.075	+0.905	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.152	+0.789	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Positive regulation of type 2 mitophagy →	+0.167	+1.082	<.001	<.001	3	15
SOFT_TISSUE	Regulation of protein sumoylation →	+0.120	+0.695	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Type 2 mitophagy →	+0.227	+0.968	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,543 associations by consensus.

Growth hormone secretion by TBC1D25 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →