TBC1D23

Across TCGA cell cohorts, TBC1D23 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,436 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TBC1D23-associated GO terms across cancer lineages are Vesicle tethering to Golgi, Maintenance of location, and Negative regulation of autophagosome assembly. Each is linked with TBC1D23 in more than 18 cancer types. Because this analysis shows association rather than direction, both TBC1D23-to-partner and partner-to-TBC1D23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering to Golgi grouped by TBC1D23-low versus TBC1D23-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D23→partner) and Y-score (partner→TBC1D23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Vesicle tethering to Golgi →	+0.113	+0.766	<.001	<.001	3	19
LIVER	Maintenance of location →	+0.073	+0.670	<.001	.001	3	13
BONE	Negative regulation of autophagosome assembly →	+0.189	+1.153	.001	<.001	3	13
LIVER	Maintenance of protein location →	+0.149	+0.724	<.001	.001	3	12
STOMACH	Maintenance of location in cell →	+0.083	+0.727	.004	.009	2	13
LUNG_NSCLC_LUAD	Negative regulation of macroautophagy →	+0.061	+0.565	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,436 associations by consensus.

Vesicle tethering to Golgi by TBC1D23 expression — STOMACH

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