TBC1D22A-AS1

Across TCGA pan-cancer cohorts, TBC1D22A-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated TBC1D22A-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TBC1D22A-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TBC1D22A-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

HNSC, KIRP, and CESC are the cancer types where TBC1D22A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.789	0.666	.002	71	view →
KIRP	OS	Tertile	III,IV	0.111	0.610	<.001	69	view →
CESC	DFS	Median	II,III,IV	0.812	0.607	.005	52	view →
ACC	DFS	Tertile	All	0.193	0.527	.013	43	view →
LUAD	OS	Median	III,IV	0.416	0.195	.002	24	view →
LGG	OS	Median	All	0.975	0.851	<.001	20	view →
UVM	OS	Quartile	III,IV	0.185	0.870	.002	15	view →
SARC	OS	Tertile	All	0.884	0.656	.003	14	view →
SKCM	DFS	Tertile	All	0.686	0.586	.015	13	view →
CHOL	DFS	Tertile	All	0.864	0.271	.014	11	view →
LAML	DFS	Median	All	0.692	0.458	.023	10	view →
PAAD	DFS	Tertile	III,IV	0.152	0.821	.045	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

TBC1D22A-AS1–HNSC (DFS)

Open the HNSC breakdown →