TBC1D21

Across TCGA patient cohorts, TBC1D21 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,448 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TBC1D21-associated GO terms across cancer lineages are Negative regulation of cell growth, Microtubule polymerization, and Cytoplasmic translation. Each is linked with TBC1D21 in more than 10 cancer types. Because this analysis shows association rather than direction, both TBC1D21-to-partner and partner-to-TBC1D21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell growth grouped by TBC1D21-low versus TBC1D21-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D21→partner) and Y-score (partner→TBC1D21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of cell growth →	+0.038	+0.083	<.001	<.001	3	11
STAD	Microtubule polymerization →	+0.055	+0.099	<.001	<.001	3	11
STAD	Cytoplasmic translation →	+0.076	+0.078	<.001	<.001	3	11
SCLC	Ribose phosphate biosynthetic process →	+0.067	+0.015	.005	.002	3	11
STAD	Regulation of calcium ion export across plasma membrane →	+0.043	+0.083	<.001	<.001	3	10
STAD	Hematopoietic or lymphoid organ development →	+0.043	+0.079	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,448 associations by consensus.

Negative regulation of cell growth by TBC1D21 expression — STAD

Explore this box plot interactively →