TBC1D20

Across TCGA patient cohorts, TBC1D20 protein abundance is significantly associated with the RNA expression of many other genes, with 6,911 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D20-associated genes across cancer lineages are DNPH1, COL5A1, and RPL30. Each is linked with TBC1D20 in more than 3 cancer types. Because this analysis shows association rather than direction, both TBC1D20-to-partner and partner-to-TBC1D20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D20 versus DNPH1 in UCEC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D20→partner) and Y-score (partner→TBC1D20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DNPH1 →	-1.320	-0.293	<.001	<.001	3	4
OV	COL5A1 →	+1.497	+0.400	.001	<.001	3	4
UCEC	RPL30 →	-1.046	-0.199	<.001	<.001	3	4
CCRCC	COL1A2 →	+1.516	+0.314	<.001	<.001	3	4
CCRCC	COL3A1 →	+1.555	+0.328	<.001	<.001	3	4
OV	MEIS3 →	+0.804	+0.292	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,911 associations by consensus.

TBC1D20 vs DNPH1 — UCEC

Explore this scatter interactively →