TBC1D20

Across TCGA cell cohorts, TBC1D20 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBC1D20-associated genes across cancer lineages are HTR3D and IL20. Each is linked with TBC1D20 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D20-to-partner and partner-to-TBC1D20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR3D grouped by TBC1D20-low versus TBC1D20-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D20→partner) and Y-score (partner→TBC1D20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HTR3D →	+0.019	+5.539	<.001	.003	3	1
LARGE_INTESTINE	IL20 →	+0.176	+3.662	.003	.009	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

HTR3D by TBC1D20 expression — BLOOD_Leukemia

Explore this box plot interactively →