TBC1D17

Across TCGA patient cohorts, TBC1D17 protein abundance is significantly associated with the RNA expression of many other genes, with 19,686 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TBC1D17-associated genes across cancer lineages are CCNB1, KIF2C, and RPL39L. Each is linked with TBC1D17 in more than 7 cancer types. Because this analysis shows association rather than direction, both TBC1D17-to-partner and partner-to-TBC1D17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D17 versus CCNB1 in LUAD, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D17→partner) and Y-score (partner→TBC1D17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CCNB1 →	-1.076	-0.265	<.001	<.001	3	8
BRCA	KIF2C →	-1.165	-0.439	<.001	<.001	3	8
HNSC	RPL39L →	-1.348	-0.251	<.001	<.001	3	8
BRCA	AURKB →	-1.274	-0.477	<.001	<.001	3	8
BRCA	PRIM2 →	-0.637	-0.540	<.001	<.001	3	7
LSCC	MAD2L1 →	-0.809	-0.166	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,686 associations by consensus.

TBC1D17 vs CCNB1 — LUAD

Explore this scatter interactively →