TBC1D17

Across TCGA patient cohorts, TBC1D17 mutation is significantly associated with the RNA expression of many other genes, with 1,054 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D17-associated genes across cancer lineages are ANKRD26P2, PSMA2P1, and UQCRHP4. Each is linked with TBC1D17 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBC1D17-to-partner and partner-to-TBC1D17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD26P2 grouped by TBC1D17-low versus TBC1D17-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D17→partner) and Y-score (partner→TBC1D17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	ANKRD26P2 →	+0.054	+4.418	<.001	.001	3	2
CESC	PSMA2P1 →	+0.104	+4.148	<.001	.002	3	2
BRCA	UQCRHP4 →	+0.381	+4.423	<.001	.006	3	2
UCEC	MRPS11 →	+0.437	+3.364	.001	.004	3	2
UCEC	KTN1-AS1 →	+0.447	+3.369	<.001	.005	3	2
HNSC	ACTG1P13 →	+0.057	+6.020	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,054 associations by consensus.

ANKRD26P2 by TBC1D17 expression — CESC

Explore this box plot interactively →