TBC1D17

Across TCGA cell cohorts, TBC1D17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,299 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TBC1D17-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Regulation of macroautophagy. Each is linked with TBC1D17 in more than 17 cancer types. Because this analysis shows association rather than direction, both TBC1D17-to-partner and partner-to-TBC1D17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by TBC1D17-low versus TBC1D17-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D17→partner) and Y-score (partner→TBC1D17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Process utilizing autophagic mechanism →	+0.079	+0.950	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Autophagy →	+0.079	+0.950	<.001	<.001	3	18
STOMACH	Regulation of macroautophagy →	+0.083	+1.175	.002	.001	3	18
LUNG_NSCLC_LUSC	Macroautophagy →	+0.076	+0.988	.002	.001	3	17
SOFT_TISSUE	Vacuolar transport →	+0.057	+0.858	<.001	<.001	3	16
LARGE_INTESTINE	Retrograde transport, endosome to Golgi →	+0.072	+0.976	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,299 associations by consensus.

Process utilizing autophagic mechanism by TBC1D17 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →