TBC1D14

Across TCGA pan-cancer cohorts, TBC1D14 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TBC1D14 data layer compared with 23 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher TBC1D14 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TBC1D14 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LIHC, ESCA, and BLCA are the cancer types where TBC1D14 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.127	0.786	<.001	15	view →
ESCA	OS	Median	All	0.095	0.701	<.001	12	view →
BLCA	OS	Median	IV	0.153	0.599	.018	9	view →
UCEC	DFS	Median	All	0.935	0.626	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TBC1D14–LIHC (OS)

Open the LIHC breakdown →