TBC1D14

Across TCGA patient cohorts, TBC1D14 mutation is significantly associated with the RNA expression of many other genes, with 3,190 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D14-associated genes across cancer lineages are BPY2DP, RN7SL398P, and MIR4504. Each is linked with TBC1D14 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBC1D14-to-partner and partner-to-TBC1D14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPY2DP grouped by TBC1D14-low versus TBC1D14-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D14→partner) and Y-score (partner→TBC1D14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BPY2DP →	+0.199	+5.409	<.001	<.001	3	3
LUSC	RN7SL398P →	+0.126	+4.235	.001	.003	3	2
LUSC	MIR4504 →	+0.360	+4.834	.001	<.001	3	2
UCEC	PFAS →	+0.434	+1.934	.001	.002	3	2
UCEC	PRF1 →	+0.901	+2.243	<.001	<.001	3	2
UCEC	TIGIT →	+0.798	+3.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,190 associations by consensus.

BPY2DP by TBC1D14 expression — COAD

Explore this box plot interactively →