TBC1D14

Across TCGA cell cohorts, TBC1D14 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,142 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TBC1D14-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, Regulation of aggrephagy, and Establishment of spindle localization. Each is linked with TBC1D14 in more than 14 cancer types. Because this analysis shows association rather than direction, both TBC1D14-to-partner and partner-to-TBC1D14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by TBC1D14-low versus TBC1D14-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D14→partner) and Y-score (partner→TBC1D14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transcription pausing by RNA polymerase II →	+0.135	+0.924	.001	.002	3	15
BREAST	Regulation of aggrephagy →	+0.169	+0.678	<.001	.002	3	14
SOFT_TISSUE	Establishment of spindle localization →	+0.101	+0.766	<.001	.001	3	12
SOFT_TISSUE	Establishment of spindle orientation →	+0.105	+0.827	<.001	<.001	3	12
BONE	Symbiont-mediated disruption of host cell PML body →	+0.102	+0.972	<.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of CAMKK-AMPK signaling cascade →	+0.921	+1.005	.001	.006	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,142 associations by consensus.

Transcription pausing by RNA polymerase II by TBC1D14 expression — LUNG_NSCLC_LUSC

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