TBC1D12

Across TCGA patient cohorts, TBC1D12 protein abundance is significantly associated with the RNA expression of many other genes, with 4,415 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TBC1D12-associated genes across cancer lineages are SEC23IP, ATE1, and COX15. Each is linked with TBC1D12 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBC1D12-to-partner and partner-to-TBC1D12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D12 versus SEC23IP in BRCA, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D12→partner) and Y-score (partner→TBC1D12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEC23IP →	+0.435	+0.307	<.001	.001	3	3
BRCA	ATE1 →	+0.593	+0.404	<.001	<.001	3	3
BRCA	COX15 →	+0.433	+0.416	<.001	<.001	3	3
HNSC	PDK4 →	+1.993	+1.164	<.001	<.001	3	3
HNSC	LDB3 →	+1.274	+0.967	<.001	<.001	3	3
HNSC	LRRC39 →	+1.272	+1.024	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,415 associations by consensus.

TBC1D12 vs SEC23IP — BRCA

Explore this scatter interactively →