TBC1D12

Across TCGA cell cohorts, TBC1D12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,715 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TBC1D12-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Golgi to plasma membrane transport, and Golgi vesicle transport. Each is linked with TBC1D12 in more than 12 cancer types. Because this analysis shows association rather than direction, both TBC1D12-to-partner and partner-to-TBC1D12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by TBC1D12-low versus TBC1D12-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D12→partner) and Y-score (partner→TBC1D12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Post-Golgi vesicle-mediated transport →	+0.045	+0.418	.001	<.001	3	13
LUNG_SCLC	Golgi to plasma membrane transport →	+0.065	+0.501	.001	.003	3	10
BLOOD_Lymphoma	Golgi vesicle transport →	+0.040	+0.866	.002	.003	3	10
BLOOD_Lymphoma	Regulation of cellular response to hypoxia →	+0.107	+1.218	<.001	<.001	3	9
BONE	Positive regulation of mitochondrial calcium ion concentration →	+0.161	+1.273	<.001	.006	3	9
UPPER_AERODIGESTIVE_TRACT	Monoubiquitinated protein deubiquitination →	+0.090	+0.573	<.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,715 associations by consensus.

Post-Golgi vesicle-mediated transport by TBC1D12 expression — LUNG_SCLC

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