TBC1D10A

Across TCGA patient cohorts, TBC1D10A mutation is significantly associated with the RNA expression of many other genes, with 1,481 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D10A-associated genes across cancer lineages are LSM3, PITHD1, and CCNT2P1. Each is linked with TBC1D10A in more than 2 cancer types. Because this analysis shows association rather than direction, both TBC1D10A-to-partner and partner-to-TBC1D10A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM3 grouped by TBC1D10A-low versus TBC1D10A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D10A→partner) and Y-score (partner→TBC1D10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSM3 →	+0.637	+3.732	.001	<.001	3	3
UCEC	PITHD1 →	+0.393	+3.387	.005	.004	3	3
LGG	CCNT2P1 →	+0.052	+6.363	<.001	.001	3	2
LUAD	MIR515-2 →	+0.958	+7.930	<.001	.008	3	2
LUAD	RPS29P26 →	+0.348	+7.930	<.001	.008	3	2
LUAD	RNU6-165P →	+0.528	+7.930	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,481 associations by consensus.

LSM3 by TBC1D10A expression — UCEC

Explore this box plot interactively →