TBC1D10A

Across TCGA cell cohorts, TBC1D10A mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBC1D10A-associated genes across cancer lineages are NEUROD6, OR1M1, and KRTAP4-4. Each is linked with TBC1D10A in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D10A-to-partner and partner-to-TBC1D10A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NEUROD6 grouped by TBC1D10A-low versus TBC1D10A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D10A→partner) and Y-score (partner→TBC1D10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	NEUROD6 →	+0.006	+5.643	.003	.002	3	1
BLOOD_Lymphoma	OR1M1 →	+0.019	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	KRTAP4-4 →	+0.022	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	CCL11 →	+0.028	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR10K1 →	+0.012	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR9A2 →	+0.029	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

NEUROD6 by TBC1D10A expression — BLOOD_Lymphoma

Explore this box plot interactively →