TBC1D1

Across TCGA patient cohorts, TBC1D1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,583 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TBC1D1-associated proteins across cancer lineages are TBC1D1_S237, TBC1D1_S695, and PYCR2. Each is linked with TBC1D1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TBC1D1-to-partner and partner-to-TBC1D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D1 versus TBC1D1_S237 in BRCA, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D1→partner) and Y-score (partner→TBC1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TBC1D1_S237 →	+0.715	+0.715	<.001	<.001	3	7
GBM	TBC1D1_S695 →	+0.812	+0.742	<.001	<.001	3	6
BRCA	PYCR2 →	-0.610	-0.575	<.001	.002	3	5
UCEC	TBC1D1_T652 →	+0.780	+0.825	<.001	<.001	3	5
HNSC	NES →	+0.795	+0.530	<.001	<.001	3	5
HNSC	NES_S680 →	+0.755	+0.557	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,583 associations by consensus.

TBC1D1 vs TBC1D1_S237 — BRCA

Explore this scatter interactively →