TBC1D1

Across TCGA patient cohorts, TBC1D1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,021 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TBC1D1-associated genes across cancer lineages are SAMHD1, PTTG2, and LILRB1. Each is linked with TBC1D1 in more than 8 cancer types. Because this analysis shows association rather than direction, both TBC1D1-to-partner and partner-to-TBC1D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D1 versus SAMHD1 in HNSC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D1→partner) and Y-score (partner→TBC1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SAMHD1 →	+0.978	+0.372	<.001	<.001	3	9
UCEC	PTTG2 →	+0.766	+0.415	<.001	<.001	3	9
BRCA	LILRB1 →	+0.742	+0.330	<.001	.004	3	8
COAD	NKG7 →	+1.437	+0.495	<.001	<.001	3	8
OV	IL10RA →	+1.065	+0.562	<.001	<.001	3	8
HNSC	CD48 →	+0.963	+0.333	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,021 associations by consensus.

TBC1D1 vs SAMHD1 — HNSC

Explore this scatter interactively →