TBATA

Across TCGA patient cohorts, TBATA mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBATA-associated genes across cancer lineages are C-Raf, Cyclin-E2, and Gab2. Each is linked with TBATA in more than 2 cancer types. Because this analysis shows association rather than direction, both TBATA-to-partner and partner-to-TBATA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C-Raf grouped by TBATA-low versus TBATA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBATA→partner) and Y-score (partner→TBATA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C-Raf →	+0.132	+1.584	.018	.036	3	3
UCEC	Cyclin-E2 →	+0.175	+2.000	.008	.010	3	3
UCEC	Gab2 →	+0.319	+1.584	.022	.036	3	2
UCEC	mTOR_pS2448 →	-0.166	-2.680	.004	.006	3	2
UCEC	Notch1 →	+0.175	+1.884	.001	.030	3	2
UCEC	ASNS →	+0.443	+2.000	.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

C-Raf by TBATA expression — UCEC

Explore this box plot interactively →