TBATA

Across TCGA cell cohorts, TBATA mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TBATA-associated genes across cancer lineages are PNLIPRP1, SMIM9, and OR52B2. Each is linked with TBATA in more than 1 cancer types. Because this analysis shows association rather than direction, both TBATA-to-partner and partner-to-TBATA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PNLIPRP1 grouped by TBATA-low versus TBATA-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBATA→partner) and Y-score (partner→TBATA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PNLIPRP1 →	+0.031	+4.450	<.001	.004	3	2
CNS	SMIM9 →	+0.032	+5.754	<.001	.002	3	1
CNS	OR52B2 →	+0.048	+4.981	<.001	.008	3	1
CNS	GUCA2B →	+0.043	+4.981	<.001	.008	3	1
OVARY	SCGB1D4 →	+0.097	+4.807	<.001	.003	3	1
SKIN	EDDM3A →	+0.021	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

PNLIPRP1 by TBATA expression — OVARY

Explore this box plot interactively →