Across TCGA pan-cancer cohorts, TAX1BP3 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TAX1BP3 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TAX1BP3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TAX1BP3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where TAX1BP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.981	0.812	.003	47	view →
LSCC	DFS	Tertile	All	0.595	0.833	.008	19	view →
LUAD	DFS	Tertile	All	1.000	0.463	.002	16	view →
GBM	DFS	Tertile	All	0.600	0.905	.001	13	view →
PDAC	DFS	Quartile	All	0.876	0.705	.009	9	view →
UCEC	OS	Quartile	III,IV	0.432	1.000	.036	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: TAX1BP3 tumor-vs-normal RNA expression · all TAX1BP3 data types