Across TCGA patient cohorts, TAX1BP3 mutation is significantly associated with the RNA expression of many other genes, with 116 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAX1BP3-associated genes across cancer lineages are NCAPD3, GPATCH11, and HEATR3. Each is linked with TAX1BP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAX1BP3-to-partner and partner-to-TAX1BP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAX1BP3→partner) and Y-score (partner→TAX1BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPD3 →	+0.700	+3.332	.008	.005	3	1
UCEC	GPATCH11 →	+0.647	+3.332	.001	.005	3	1
UCEC	HEATR3 →	+0.641	+3.332	.002	.005	3	1
UCEC	MAPK9 →	+0.474	+3.332	.007	.005	3	1
UCEC	MKNK2 →	+0.744	+3.332	.001	.005	3	1
SKCM	RNU7-195P →	+0.565	+5.771	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 116 associations by consensus.

Exploration

TAX1BP3 survival (RNA) · tumor vs normal (RNA) · all TAX1BP3 data types