TAX1BP1

Across TCGA pan-cancer cohorts, TAX1BP1 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TAX1BP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where TAX1BP1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types TAX1BP1 is over-expressed in tumor, although a few such as HNSC and CCRCC show the opposite, repressed pattern.

LUAD, HNSC, and CCRCC are the cancer types where TAX1BP1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAX1BP1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	+0.834	<.001	9	view →
HNSC	Male	IV	−0.509	<.001	8	view →
CCRCC	Male	IV	−0.573	<.001	7	view →
LSCC	Male	All	+0.327	<.001	7	view →
COAD	Female	All	+0.258	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

TAX1BP1–LUAD

Open the LUAD breakdown →