Across TCGA patient cohorts, TATDN3 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TATDN3-associated genes across cancer lineages are Heregulin, p38-MAPK_pT180_Y182, and Annexin_VII. Each is linked with TATDN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TATDN3-to-partner and partner-to-TATDN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TATDN3→partner) and Y-score (partner→TATDN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Heregulin →	-0.150	-3.000	.026	.036	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.686	-3.156	.005	.020	3	1
UCEC	Annexin_VII →	-0.195	-3.169	.010	.020	3	1
UCEC	Shc_pY317 →	-0.318	-3.169	<.001	.019	3	1
UCEC	FoxM1 →	+0.321	+3.169	.023	.020	2	1
UCEC	Smad3 →	+0.191	+3.169	.021	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

TATDN3 survival (RNA) · tumor vs normal (RNA) · all TATDN3 data types