TATDN2

Across TCGA cell cohorts, TATDN2 mutation is significantly associated with the RNA expression of many other genes, with 447 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TATDN2-associated genes across cancer lineages are FOLH1, UGT3A1, and GPR171. Each is linked with TATDN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TATDN2-to-partner and partner-to-TATDN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOLH1 grouped by TATDN2-low versus TATDN2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TATDN2→partner) and Y-score (partner→TATDN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FOLH1 →	+1.428	+2.906	<.001	.001	3	2
URINARY_TRACT	UGT3A1 →	+0.053	+4.217	<.001	.005	3	1
URINARY_TRACT	GPR171 →	+0.025	+4.217	<.001	.005	3	1
URINARY_TRACT	SRARP →	+0.006	+4.217	<.001	.005	3	1
URINARY_TRACT	OR52K1 →	+0.005	+4.087	<.001	.009	3	1
URINARY_TRACT	LRIT2 →	+0.027	+4.087	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 447 associations by consensus.

FOLH1 by TATDN2 expression — LARGE_INTESTINE

Explore this box plot interactively →