TAT-AS1

Across TCGA pan-cancer cohorts, TAT-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated TAT-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher TAT-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TAT-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and LIHC show a favorable association.

MESO, LIHC, and PAAD are the cancer types where TAT-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.490	0.276	<.001	62	view →
LIHC	OS	Quartile	All	0.851	0.710	.003	38	view →
PAAD	DFS	Quartile	All	0.469	0.159	.001	29	view →
BRCA	OS	Tertile	All	0.642	0.496	.009	18	view →
STAD	DFS	Median	IV	0.154	0.566	.002	18	view →
SARC	DFS	Tertile	All	0.749	0.508	.002	15	view →
UVM	OS	Median	All	1.000	0.784	.017	14	view →
KIRC	OS	Quartile	All	0.507	0.739	.006	13	view →
COAD	DFS	Tertile	II,III,IV	0.360	0.513	.017	12	view →
TGCT	DFS	Median	All	0.925	0.738	.008	12	view →
CESC	DFS	Median	All	0.776	0.861	.006	8	view →
LUAD	DFS	Quartile	IV	0.243	0.741	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

TAT-AS1–MESO (OS)

Open the MESO breakdown →