TASP1

Across TCGA cell cohorts, TASP1 mutation is significantly associated with the mutation status of many other genes, with 5,628 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TASP1-associated genes across cancer lineages are FRMD5, RUVBL1, and RIPOR1. Each is linked with TASP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TASP1-to-partner and partner-to-TASP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FRMD5 grouped by TASP1-low versus TASP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TASP1→partner) and Y-score (partner→TASP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FRMD5 →	+6.169	+6.169	<.001	<.001	1	4
BLOOD_Lymphoma	RUVBL1 →	+5.584	+5.014	.003	.003	1	4
BLOOD_Lymphoma	RIPOR1 →	+4.584	+4.584	.007	.007	1	4
SKIN	PRKN →	+5.824	+5.824	.002	.002	1	4
BLOOD_Leukemia	LMTK3 →	+3.145	+3.932	.004	.004	1	4
LARGE_INTESTINE	ACOX1 →	+3.807	+3.137	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,628 associations by consensus.

FRMD5 by TASP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →