TASOR

Across TCGA pan-cancer cohorts, TASOR mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TASOR data layer compared with 20 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TASOR mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TASOR expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

HNSC, LUAD, and UCEC are the cancer types where TASOR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.648	0.926	<.001	77	view →
LUAD	DFS	Median	All	0.975	0.857	.004	25	view →
UCEC	DFS	Tertile	II,III,IV	0.535	1.000	.008	20	view →
GBM	OS	Median	All	0.636	0.440	.002	12	view →
PDAC	OS	Median	II,III,IV	0.403	0.675	.003	4	view →
CCRCC	DFS	Median	All	0.843	0.661	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TASOR–HNSC (DFS)

Open the HNSC breakdown →