TASOR

Across TCGA patient cohorts, TASOR protein abundance is significantly associated with the RNA expression of many other genes, with 11,052 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TASOR-associated genes across cancer lineages are NPRL2, RFT1, and CCDC66. Each is linked with TASOR in more than 5 cancer types. Because this analysis shows association rather than direction, both TASOR-to-partner and partner-to-TASOR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TASOR versus NPRL2 in BRCA, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TASOR→partner) and Y-score (partner→TASOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NPRL2 →	+0.555	+0.251	<.001	<.001	3	6
BRCA	RFT1 →	+0.371	+0.176	<.001	<.001	3	6
BRCA	CCDC66 →	+0.513	+0.173	<.001	<.001	3	6
BRCA	CNOT10 →	+0.410	+0.209	<.001	<.001	3	6
UCEC	SLC25A38 →	+0.935	+0.126	.001	.003	3	5
GBM	LIMD1 →	+0.494	+0.199	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,052 associations by consensus.

TASOR vs NPRL2 — BRCA

Explore this scatter interactively →