TASOR

Across TCGA cell cohorts, TASOR mutation is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TASOR-associated genes across cancer lineages are APOBEC1, WNT1, and OR2M3. Each is linked with TASOR in more than 1 cancer types. Because this analysis shows association rather than direction, both TASOR-to-partner and partner-to-TASOR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APOBEC1 grouped by TASOR-low versus TASOR-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TASOR→partner) and Y-score (partner→TASOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	APOBEC1 →	+0.019	+3.584	<.001	.005	3	1
URINARY_TRACT	WNT1 →	+0.058	+3.807	.001	.005	3	1
BREAST	OR2M3 →	+0.006	+5.169	<.001	.005	3	1
STOMACH	OR2F1 →	+0.050	+4.129	<.001	.007	3	1
OVARY	KRTAP10-5 →	+0.013	+5.807	<.001	.001	3	1
LARGE_INTESTINE	SDC4 →	-1.415	-3.169	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

APOBEC1 by TASOR expression — URINARY_TRACT

Explore this box plot interactively →