TAS2R9

Across TCGA cell cohorts, TAS2R9 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,007 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TAS2R9-associated GO terms across cancer lineages are Positive regulation of cell fate commitment, Positive regulation of T-helper 17 cell lineage commitment, and Regulation of RNA polymerase II transcription preinitiation complex assembly. Each is linked with TAS2R9 in more than 5 cancer types. Because this analysis shows association rather than direction, both TAS2R9-to-partner and partner-to-TAS2R9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell fate commitment grouped by TAS2R9-low versus TAS2R9-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R9→partner) and Y-score (partner→TAS2R9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of cell fate commitment →	+0.131	+0.027	.006	.002	2	6
BONE	Positive regulation of T-helper 17 cell lineage commitment →	+0.110	+0.033	.003	.005	3	5
BLOOD_Leukemia	Regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.080	+0.016	.001	.005	3	5
SKIN	Viral gene expression →	+0.077	+0.018	<.001	.004	3	5
OVARY	Anaphase-promoting complex-dependent catabolic process →	+0.047	+0.032	.005	.005	3	5
CNS	Negative regulation of tRNA metabolic process →	+0.077	+0.018	.003	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,007 associations by consensus.

Positive regulation of cell fate commitment by TAS2R9 expression — OVARY

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