TAS2R6P

Across TCGA pan-cancer cohorts, TAS2R6P RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated TAS2R6P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TAS2R6P RNA is associated with better overall survival. In most high-consensus cancer types, elevated TAS2R6P expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

HNSC, READ, and CESC are the cancer types where TAS2R6P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.585	0.274	<.001	76	view →
READ	OS	Median	All	0.965	0.855	.001	46	view →
CESC	DFS	Tertile	All	0.764	0.894	.001	44	view →
MESO	DFS	Median	All	0.242	0.605	.007	33	view →
LIHC	OS	Quartile	III,IV	0.345	0.642	.007	30	view →
UCS	DFS	Tertile	IV	0.932	0.484	.024	24	view →
KIRC	DFS	Tertile	All	0.457	0.695	.006	15	view →
LUAD	DFS	Tertile	IV	0.406	1.000	.014	15	view →
PRAD	DFS	Tertile	All	0.650	0.808	.010	14	view →
BRCA	DFS	Quartile	All	0.965	0.922	.014	12	view →
GBM	DFS	Quartile	All	0.532	0.213	.007	12	view →
CHOL	OS	Median	IV	0.208	0.948	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

TAS2R6P–HNSC (OS)

Open the HNSC breakdown →