TAS2R43

Across TCGA cell cohorts, TAS2R43 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAS2R43-associated genes across cancer lineages are FAM9A and PRAMEF7. Each is linked with TAS2R43 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R43-to-partner and partner-to-TAS2R43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM9A grouped by TAS2R43-low versus TAS2R43-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R43→partner) and Y-score (partner→TAS2R43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FAM9A →	+0.014	+4.539	<.001	.007	3	1
BLOOD_Leukemia	PRAMEF7 →	+0.022	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FAM9A by TAS2R43 expression — BLOOD_Leukemia

Explore this box plot interactively →