Across TCGA patient cohorts, TAS2R42 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,717 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TAS2R42-associated proteins across cancer lineages are ZC3H4, SMARCA1, and SNW1. Each is linked with TAS2R42 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAS2R42-to-partner and partner-to-TAS2R42 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R42→partner) and Y-score (partner→TAS2R42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZC3H4 →	+0.186	+0.319	.003	.002	3	3
HNSC	SMARCA1 →	+0.417	+0.379	.002	.003	3	3
GBM	SNW1 →	+0.193	+0.322	<.001	<.001	3	3
GBM	ALYREF →	+0.275	+0.377	.001	<.001	3	3
GBM	HNRNPK →	+0.276	+0.422	<.001	<.001	3	3
GBM	MORF4L1 →	+0.286	+0.403	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,717 associations by consensus.

Exploration

TAS2R42 survival (RNA) · tumor vs normal (RNA) · all TAS2R42 data types