Across TCGA cell cohorts, TAS2R41 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TAS2R41-associated genes across cancer lineages are OR4X2, IFNA14, and MBD3L5. Each is linked with TAS2R41 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R41-to-partner and partner-to-TAS2R41 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R41→partner) and Y-score (partner→TAS2R41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR4X2 →	+0.032	+5.369	<.001	.004	3	1
SOFT_TISSUE	IFNA14 →	+0.032	+5.369	<.001	.004	3	1
SKIN	MBD3L5 →	+0.029	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

TAS2R41 survival (RNA) · tumor vs normal (RNA) · all TAS2R41 data types