TAS2R39

Across TCGA patient cohorts, TAS2R39 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,184 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TAS2R39-associated proteins across cancer lineages are FAM126A_S453, SMC3, and SYTL1. Each is linked with TAS2R39 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAS2R39-to-partner and partner-to-TAS2R39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAS2R39 versus FAM126A_S453 in HNSC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R39→partner) and Y-score (partner→TAS2R39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FAM126A_S453 →	-0.672	-0.299	<.001	.005	3	3
LSCC	SMC3 →	+0.350	+0.639	<.001	<.001	3	3
UCEC	SYTL1 →	-0.420	-0.490	<.001	.002	3	3
LSCC	COPG1 →	-0.275	-0.637	<.001	<.001	3	3
LSCC	LRWD1_S212 →	+0.597	+0.484	.002	.001	3	3
HNSC	MAP1S_T941 →	+0.559	+0.435	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,184 associations by consensus.

TAS2R39 vs FAM126A_S453 — HNSC

Explore this scatter interactively →