Across TCGA patient cohorts, TAS2R38 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,798 significant associations in total. THYM shows the largest number of these associations.

The most reproducible TAS2R38-associated GO terms across cancer lineages are Regulation of proteolysis involved in protein catabolic process, Regulation of ubiquitin-dependent protein catabolic process, and Regulation of double-strand break repair via homologous recombination. Each is linked with TAS2R38 in more than 18 cancer types. Because this analysis shows association rather than direction, both TAS2R38-to-partner and partner-to-TAS2R38 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R38→partner) and Y-score (partner→TAS2R38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of proteolysis involved in protein catabolic process →	+0.052	+0.317	<.001	<.001	3	19
THYM	Regulation of ubiquitin-dependent protein catabolic process →	+0.041	+0.458	<.001	<.001	3	19
LIHC	Regulation of double-strand break repair via homologous recombination →	+0.040	+0.059	<.001	<.001	3	19
THYM	Epigenetic regulation of gene expression →	+0.043	+0.499	<.001	<.001	3	19
LIHC	Regulation of microtubule polymerization →	+0.034	+0.046	<.001	<.001	3	19
THYM	Regulation of intracellular protein transport →	+0.036	+0.888	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,798 associations by consensus.

Exploration

TAS2R38 survival (RNA) · tumor vs normal (RNA) · all TAS2R38 data types