TAS2R38

Across TCGA cell cohorts, TAS2R38 RNA expression is significantly associated with the RNA expression of many other genes, with 3,649 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TAS2R38-associated genes across cancer lineages are CBY2, KRTAP4-1, and ELMO3. Each is linked with TAS2R38 in more than 6 cancer types. Because this analysis shows association rather than direction, both TAS2R38-to-partner and partner-to-TAS2R38 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAS2R38 versus CBY2 in BLOOD_Myeloma, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R38→partner) and Y-score (partner→TAS2R38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CBY2 →	+1.010	+0.650	.001	.002	2	7
OESOPHAGUS	KRTAP4-1 →	+0.808	+0.503	<.001	.002	2	7
LUNG_NSCLC_LUSC	ELMO3 →	+1.880	+0.305	<.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	PHYKPL →	+0.998	+0.424	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	RUSF1 →	+0.720	+0.404	<.001	.001	3	4
OESOPHAGUS	RNF44 →	+0.997	+0.629	<.001	.002	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,649 associations by consensus.

TAS2R38 vs CBY2 — BLOOD_Myeloma

Explore this scatter interactively →