TAS2R38

Across TCGA cell cohorts, TAS2R38 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TAS2R38-associated genes across cancer lineages are SPATA31D4. Each is linked with TAS2R38 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R38-to-partner and partner-to-TAS2R38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31D4 grouped by TAS2R38-low versus TAS2R38-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R38→partner) and Y-score (partner→TAS2R38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SPATA31D4 →	+0.069	+2.977	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SPATA31D4 by TAS2R38 expression — SKIN

Explore this box plot interactively →