TAS2R3

Across TCGA patient cohorts, TAS2R3 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,845 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TAS2R3-associated proteins across cancer lineages are THRAP3_S339, RBBP5_S350, and RBM12B. Each is linked with TAS2R3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R3-to-partner and partner-to-TAS2R3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAS2R3 versus THRAP3_S339 in LUAD, with a Pearson correlation of 0.63.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R3→partner) and Y-score (partner→TAS2R3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	THRAP3_S339 →	+0.506	+0.831	.001	.002	3	2
LUAD	RBBP5_S350 →	+0.583	+0.548	<.001	.001	3	1
LUAD	RBM12B →	+0.199	+0.521	<.001	<.001	3	1
LUAD	RBM12B_S562 →	+0.615	+0.583	<.001	<.001	3	1
LUAD	RBM12B_S718 →	+0.519	+0.748	.003	.004	3	1
LUAD	RBM15_S80 →	+0.350	+0.482	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,845 associations by consensus.

TAS2R3 vs THRAP3_S339 — LUAD

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