TAS2R3

Across TCGA cell cohorts, TAS2R3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,300 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAS2R3-associated GO terms across cancer lineages are Oocyte growth, Cilium or flagellum-dependent cell motility, and Cilium-dependent cell motility. Each is linked with TAS2R3 in more than 14 cancer types. Because this analysis shows association rather than direction, both TAS2R3-to-partner and partner-to-TAS2R3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oocyte growth grouped by TAS2R3-low versus TAS2R3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R3→partner) and Y-score (partner→TAS2R3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Oocyte growth →	+0.252	+0.201	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.131	-0.287	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.131	-0.287	<.001	<.001	3	14
BONE	Viral translational termination-reinitiation →	+0.094	+0.292	<.001	.004	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.138	-0.287	<.001	<.001	3	13
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.188	+0.202	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,300 associations by consensus.

Oocyte growth by TAS2R3 expression — BONE

Explore this box plot interactively →