TAS2R20

Across TCGA patient cohorts, TAS2R20 mutation is significantly associated with the RNA expression of many other genes, with 550 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAS2R20-associated genes across cancer lineages are MIR4797, MIR4449, and RNA5SP325. Each is linked with TAS2R20 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAS2R20-to-partner and partner-to-TAS2R20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4797 grouped by TAS2R20-low versus TAS2R20-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R20→partner) and Y-score (partner→TAS2R20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR4797 →	+0.631	+3.642	<.001	.009	3	3
UCEC	MIR4449 →	+0.783	+2.239	<.001	.009	3	2
UCEC	RNA5SP325 →	+0.955	+2.296	<.001	.007	3	2
BLCA	RNU6-223P →	+0.429	+5.732	<.001	<.001	3	1
BLCA	RNU6-414P →	+0.417	+3.642	<.001	.009	3	1
BLCA	RNU6-1062P →	+0.404	+3.642	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 550 associations by consensus.

MIR4797 by TAS2R20 expression — BLCA

Explore this box plot interactively →